Closed-loop control of propofol anaesthesia

Closed-loop feedback control of propofol anaesthesia by quantitative EEG analysis in humans.

Propofol was administered for 2 h to 11 volunteers by an adaptive feedback control algorithm based on quantitative EEG analysis. Median EEG frequency served as the control variable. The range 2-3 Hz was chosen as the target range of control. During the feedback period, volunteers did not respond to commands and eyelash reflex was abolished. An average median frequency of 2.5 (SD 0.3) Hz was obt...

Model identification for closed-loop control of propofol in children

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Individualized closed-loop control of propofol anesthesia: A preliminary study

This paper proposes an individualized approach to closed-loop control of depth of hypnosis during propofol anesthesia. The novelty of the paper lies in the individualization of the controller at the end of the induction phase of anesthesia, based on a patient model identified from the dose–response relationship during induction of anesthesia. The proposed approach is shown to be superior to adm...

Closed Loop Anaesthesia Delivery System (CLADS) - Anaesthesia Robot

With the advancement in microprocessor technology and development of objective anaesthesiadepth indicators, the use of automated anaesthesia deliver system using feedback from differentEEG derived parameters has become a reality. The anaesthetic drugs can be delivered based onpatients’ individual requirement using computer controlled syringe infusion pumps. CLADS is anindige...

Closed-loop Controlled Total Intra Venous Anaesthesia